Certainly there is not much to laugh at when it comes to the extermination of the bison in the American West.
I found this image from Frank Leslie's Illustrated Newspaper today. It shows men shooting at buffalo (eh, bison, buffalo, only extreme zoology pedants will get up in my grill about it) from the windows of a train - an exceptionally stupid and cruel stunt inflicted by a people already well-known for their stupidity and cruelty.
But stupid and cruel though it is, I still got a pretty dark chuckle out of it, especially having recently seen Will Smith using a Ford Shelby Mustang to hunt deer in Manhattan in I Am Legend. Call this the predecessor if you will.